Melissa Haendel is the Chief Research Informatics Officer at University of Colorado Anschutz Medical School, and Director of the Center for Data to Health (CD2H). Her background is molecular genetics, developmental biology, and toxicology as well as translational informatics, with a focus over the past decade on open science and semantic engineering. Dr. Haendel’s vision is to weave together healthcare systems, basic science research, and patient generated data through development of data integration technologies and innovative data capture strategies. Dr. Haendel’s research has focused on integration of genotype-phenotype data to improve rare disease diagnosis and mechanism discovery.