A member of the Navajo Nation, she cofounded the Native BioData Consortium. Today, Tsosie leads the Tsosie Lab for Indigenous Genomic Data Equity and Justice at ASU. One lab project involves working with Tribal partners in the Phoenix area to create a multiethnic cohort for genomic and nongenomic data. The data, which will include social, structural, cultural and traditional factors, could provide a more complex picture of health disparities and what causes them, as well as a more nuanced understanding of Indigenous identity and health.