The Chief Technology Officer at the U.S. Department of Health and Human Services is, in a lot of ways, the chief innovation officer, bringing a can-do, creative spirit to government.
Synthetic biology seeks to probe fundamental aspects of biological form and function by construction (i.e. resynthesis) rather than deconstruction (analysis). Synthesis thus complements reductionist and analytic studies of life, and allows novel approaches towards fundamental biological questions.
Duchenne muscular dystrophy (DMD) is a severe, progressive, fatal muscle disorder caused by loss-of-function mutations in the DMD gene that leads to the absence of the dystrophin protein.
How do you know your gender? From Time to People, cradle to grave, few aspects of human identity have exploded into our current collective and visible consciousness as transgender, gender variant, gender expansive, and gender creative identities across the human lifespan. Is this a new phenomenon in human development?
Elizabeth Fenn is the chair of the History Department at the University of Colorado Boulder, where she is the Walter and Lucienne Driskill Professor of Western American History.
Alexander Fleming noted the importance of drug-resistant microbes when he accepted the Nobel Prize in 1945 for the discovery of the first “wonder drug”—penicillin.
Richard Barker will explore the mystery of our persistent failure in turning great advances in bioscience into lasting and affordable patient benefit. He will lay out five ‘gaps in translation’ and a strategy to overcome each—with precision medicine the golden thread that runs through his solutions. He believes we can improve the productivity of the medical innovation process by at least an order of magnitude, if we are prepared to challenge and change our innovation ecosystem.
No microbe exists in isolation. When we become infected with a respiratory pathogen, like influenza, our bodies harbor not just the current influenza strain making the news; they share space with other drug-resistant variants and bacterial species. Together, these “bugs” set off a complex set of interactions that impact viral evolutionary dynamics and skew clinical outcome and can lead, for example, to pneumonia.
The Sawyer Lab is establishing techniques that fit into the “rapid response” pipeline on which we must now rely in the face of endless new viral emergence events.